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St. John’s Wort

Drug Interactions Safety Check

Certain medications may have beneficial or harmful interactions with St. John’s wort. Refer to the individual drugs for specific information about an interaction.

Cyclosporine (Reduced drug absorption/bioavailability *)

Digoxin (Reduced drug absorption/bioavailability *)

Fluoxetine (Adverse interaction)

Fluvoxamine (Adverse interaction *)

Indinavir (Reduced drug absorption/bioavailability)

Nefazodone (Adverse interaction *)

Oral Contraceptives (Adverse interaction *)

Paroxetine (Adverse interaction *)

Phenelzine (Adverse interaction *)

Sertraline (Adverse interaction *)

Trazodone (Adverse interaction *)

Tricyclic Antidepressants (Adverse interaction *)

Venlafaxine (Adverse interaction *)

Warfarin (Reduced drug absorption/bioavailability *)