.
Combination drug: Claritin®-D
Loratadine is a selective antihistamine used to relieve allergic rhinitis (seasonal allergy) symptoms, including sneezing, runny nose, itching, and watery eyes. It is also used to treat people with idiopathic urticaria. Loratadine is available alone and in a combination product.
Interactions with Foods and Other Compounds
Food
Food slows the absorption of loratadine and also increases the total amount of the drug
absorbed.1 It is recommended that loratadine be taken on an empty
stomach.2
Alcohol
Selective antihistamines, including loratadine, may cause drowsiness or dizziness, although it
is less likely than with nonselective antihistamines.3 Alcohol can intensify
drowsiness and dizziness, increasing the risk of accidental injury. People taking loratadine
should use alcohol only with caution.
Summary of Interactions for Loratadine
| Depletion or interference | None known |
|---|---|
| Adverse interaction | None known |
| Side effect reduction/prevention | None known |
| Supportive interaction | None known |
| Reduced drug absorption/bioavailability | None known |
For the convenience of the reader, the information in the summary is categorized as follows: “Depletion or interference” indicates the drug may deplete or interfere with the absorption or function of the supplement or herb. “Adverse interaction” indicates that the supplement or herb used together with the drug may result in undesirable effects. “Side effect reduction/prevention” indicates the supplement or herb may reduce the likelihood and/or severity of a potential side effect caused by the drug. “Supportive interaction” indicates the supplement or herb may support or aid the function of the drug. “Reduced drug absorption/bioavailability” indicates that the supplement or herb may decrease the absorption and/or activity of the drug in the body. An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
References:
1. Threlkeld DS, ed. Respiratory Drugs, Antihistamines. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1998, 194b.
2. Threlkeld DS, ed. Respiratory Drugs, Antihistamines. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1998, 194b.
3. Threlkeld DS, ed. Respiratory Drugs, Antihistamines. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1998, 194b.
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