.
Lindane lotion is used topically to treat scabies;lindane shampoo is used to treat head and pubic lice. They are used in situations where treatment with other drugs has failed or cannot be tolerated by the individual.
Interactions with Dietary Supplements
Vitamin E
Test tube studies reveal that vitamin E protects white blood cells from damage caused by
lindane.1 Lindane is known to promote the formation of tumors,2 and more
research is needed to determine whether vitamin E, when applied at the same time as lindane,
can prevent this adverse effect.
Interactions with Foods and Other Compounds
Oils
Applying oils, creams, and ointments at the same time as lindane may enhance the absorption of
the drug through the skin.3 Therefore, to avoid side effects, other drugs and
herbal formulas in cream or ointment form should be applied at other times during the day.
Summary of Interactions for Lindane
| Depletion or interference | None known |
|---|---|
| Adverse interaction | None known |
| Side effect reduction/prevention | Vitamin E* |
| Supportive interaction | None known |
| Reduced drug absorption/bioavailability | None known |
For the convenience of the reader, the information in the summary is categorized as follows: “Depletion or interference” indicates the drug may deplete or interfere with the absorption or function of the supplement or herb. “Adverse interaction” indicates that the supplement or herb used together with the drug may result in undesirable effects. “Side effect reduction/prevention” indicates the supplement or herb may reduce the likelihood and/or severity of a potential side effect caused by the drug. “Supportive interaction” indicates the supplement or herb may support or aid the function of the drug. “Reduced drug absorption/bioavailability” indicates that the supplement or herb may decrease the absorption and/or activity of the drug in the body. An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
References:
1. Podstawka U, Grabarczyk M, Kopec-Szlezak J. Vitamin E protects human leucocytes against toxic effects of lindane in vitro. Mater Med Pol 1991;23:285–9.
2. Dich J, Zahn SH, Hanberg A, Adami HO. Pesticides and cancer. Cancer Causes Control 1997;8:420–43.
3. Sifton DW, ed. Physicians Desk Reference. Montvale, NJ: Medical Economics Company, Inc.,2000, 504–5.
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The information presented in VitaminLore is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.