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Calcium-Channel Blockers

Also indexed as: Bepadin®, Bepridil, Cardene®, DynaCirc®, Isradipine, Lacidipine, Lercanidipine, Nicardipine, Nimodipine, Nimotop®, Nisoldipine, Sular®, Vascor®

Calcium-channel blockers are a family of drugs used to treat angina, high blood pressure, heart arrhythmia, heart failure, and Raynaud’s disease, as well as to prevent migraine headaches.

For interactions involving specific calcium-channel blocking drugs, refer to the highlighted medications listed below.

Interactions with Herbs

Pleurisy root
As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as calcium channel blockers.1

Summary of Interactions for Calcium Channel Blockers

Depletion or interference None known
Adverse interaction Pleurisy root
Side effect reduction/prevention None known
Supportive interaction None known
Reduced drug absorption/bioavailability None known
Interactions common to many, if not all, Calcium Channel Blockers are described in this article. Interactions reported for only one or several drugs in this class may not be listed in this article. Some drugs listed in this article are linked to articles specific to that respective drug; please refer to those individual drug articles. The information in this article may not necessarily apply to drugs in this class for which no separate article exists. If you are taking a Calcium Channel Blocker for which no separate article exists, talk with your doctor or pharmacist.

For the convenience of the reader, the information in the summary is categorized as follows: “Depletion or interference” indicates the drug may deplete or interfere with the absorption or function of the supplement or herb. “Adverse interaction” indicates that the supplement or herb used together with the drug may result in undesirable effects. “Side effect reduction/prevention” indicates the supplement or herb may reduce the likelihood and/or severity of a potential side effect caused by the drug. “Supportive interaction” indicates the supplement or herb may support or aid the function of the drug. “Reduced drug absorption/bioavailability” indicates that the supplement or herb may decrease the absorption and/or activity of the drug in the body. An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

References:

1. Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-Care Professionals. London: Pharmaceutical Press, 1996, 213–4.