.
Combination drugs: Fioricet®, Fiorinal®, Phrenilin®
Butalbital is in a class of drugs known as barbiturates and is used to treat tension headaches. There are currently no reported nutrient or herb interactions involving butalbital. See barbiturates for interactions common to this class of drugs, though they have not yet been investigated for butalbital.
Interactions with Foods and Other Compounds
Alcohol
Drinking alcoholic beverages while taking barbiturates increases side effects, such as
drowsiness, confusion, and dizziness;1 2 if taken in excess, this
combination may result in death. Consequently, people taking barbiturates should avoid
drinking alcohol.
Summary of Interactions for Butalbital
| Depletion or interference | None known |
|---|---|
| Adverse interaction | Alcohol |
| Side effect reduction/prevention | None known |
| Supportive interaction | None known |
| Reduced drug absorption/bioavailability | None known |
For the convenience of the reader, the information in the summary is categorized as follows: “Depletion or interference” indicates the drug may deplete or interfere with the absorption or function of the supplement or herb. “Adverse interaction” indicates that the supplement or herb used together with the drug may result in undesirable effects. “Side effect reduction/prevention” indicates the supplement or herb may reduce the likelihood and/or severity of a potential side effect caused by the drug. “Supportive interaction” indicates the supplement or herb may support or aid the function of the drug. “Reduced drug absorption/bioavailability” indicates that the supplement or herb may decrease the absorption and/or activity of the drug in the body. An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
References:
1. Sifton DW, ed. Physicians Desk Reference, Montvale, NJ: Medical Economics Company, Inc., 2000, 906–7.
2. Olin BR, ed. Central Nervous System Drugs, Sedatives and Hypnotics, Barbiturates. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, 1993, 1398–413.
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